陈胜良,上海交通大学医学院附属仁济医院消化内科,上海 200127, Email: chenslmd@163.com,电话:021-34506384;唐旭东,中国中医科学院西苑医院脾胃病研究所,北京 100091, Email: txdly@sina.com.cn,电话:010-64089777;侯晓华,华中科技大学同济医学院附属协和医院消化内科,武汉 430022,Email: houxh@hust.edu.cn,电话:027-85726357 Chen Shengliang, Division of Gastroenterology and Hepatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China, Email: chenslmd@163.com, Tel: 0086-21-34506384;Tang Xudong, Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, Email: txdly@sina.com.cn, Tel: 0086-10-64089777;Hou Xiaohua, Department of Gastroenterology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Email: houxh@hust.edu.cn, Tel: 0086-27-85726357
由于综合性医院消化专科医师通常接受西医教育,对中医中药的理论和辨证思维不尽了解,且舒肝解郁胶囊药品说明书中适应证内容关于消化专科症候的叙述高度概括,消化专科医师对舒肝解郁胶囊的临床应用可能存在一些困惑。为了增进中西医理论融合,提升西医消化专科医务人员应用中医、中药解决本学科临床难题的理论和实践水平,最终提升消化心身疾病临床处置水平,造福患者,中华消化心身联盟在西医消化专科领域开展了舒肝解郁胶囊临床应用困惑的问题收集项目,针对收集到的问题,邀请全国消化心身疾病领域著名专家,就现有的循证医学证据结合临床工作经验,形成了19项条目。循证医学证据主要通过检索国内外在线图书馆和数据库相关文献获得;循证医学证据不足的条目,采用专家访谈总结形成临床建议或陈述,由20名专家进行投票。使用的中文检索词为"舒(疏)肝解郁胶囊"和"疏肝解郁胶囊",英文检索词为"SGJY"和"shuganjieyu"。检索中国知网(CNKI)、万方数据、维普网期刊数据库、CBM(SinoMed)、PubMed、Embase、Web of Science、Cochrane Library等文献数据库从建库到2023年8月15日的相关文献;最终纳入系统综述、随机对照试验、观察性研究。形成的《推荐意见投票单》根据推荐等级的评估、制订与评价(grading of recommendations assessment, development, and evaluation;GRADE)分级标准(表1)分为A、B、C、D,投票采用GRADE网格计票规则,分为强推荐、弱推荐、无明确推荐、弱不推荐、强不推荐,最终以循证共识的形式呈现;对于无循证医学证据的条目,形成共识建议投票单,采用多数计票规则,分为建议、中立、不建议,最终以经验共识的形式呈现。未达成共识的陈述条目,经专家现场讨论,修正表述,进入下一轮投票,投票不超过3轮。经3轮投票仍然未通过的条目附在本共识文末,以呈现此次共识讨论的全部条目。
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